IONSIONIS PHARMACEUTICALS INC.

CUSIP: 462222100

Guru Owners

$200.4M

Total Value Held

2.5M

Total Shares

Investor	Fund	Shares	Value▼	% of Portfolio	Rpt Price	Period
Tweedy Browne	Tweedy Browne Company	2464930	$195.0M	15.74%	$79.11	Q4 2025
Ray Dalio	Bridgewater Associates	67706	$5.4M	0.02%	$79.11	Q4 2025

Tweedy Browne

$195.0M

15.74%

Ray Dalio

$5.4M

0.02%

📊 Fundamentals

Market Cap$12.3B

Forward P/E-136.3x

EPS (TTM)$-2.38

Revenue (TTM)$943.7M

Profit Margin-40.41%

Beta0.40

52-Week Range

$28.46

$86.74

Current: $74.33

Data from Yahoo Finance · refreshed every 4 hours

📊 Holdings Over Time

How superinvestor ownership has changed across quarters

Quarter-by-Quarter Activity

Q4 '252 owners · $200.4M

REDUCEDTweedy Browne$195.0M

INCREASEDRay Dalio$5.4M

Q3 '252 owners · $192.6M

INCREASEDTweedy Browne$189.8M

NEWRay Dalio$2.9M

Q2 '251 owners · $114.3M

REDUCEDTweedy Browne$114.3M

Q1 '251 owners · $90.0M

REDUCEDTweedy Browne$90.0M

Q4 '241 owners · $113.6M

REDUCEDTweedy Browne$113.6M

Q3 '241 owners · $138.4M

No changes

💰 DCF Calculator

DCF model · 10-yr forecast

Estimates depend entirely on your assumptions. Adjust the inputs below to explore scenarios.

⚠️ This company currently has negative free cash flow. The valuation assumes it will improve.

📊 Adjust the assumptions below to calculate an estimated fair value

Projection Period

Revenue Growth Rate

71%analyst est. 71.0%

0%100%

Growth Decay Rate

15%

0% (no decay)50% (fast decay)

Terminal Growth Rate

3.0%

0%5%

FCF Margin

5.0%current: -16.4%

1%50%

Discount Rate (WACC)

8.0%typical: 8% large caps · 10% growth

5%20%

Model: 10-year DCF · 3.0% terminal growth · Based on Yahoo Finance data